Ketamine for the treatment of major depression: a systematic review and meta-analysis
Read article – https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(23)00304-8/fulltext

Ketamine Assisted Psychotherapy (KAP): Patient Demographics,

Clinical Data and Outcomes in Three Large Practices Administering

Ketamine with Psychotherapy

Read the article: https://psycnet.apa.org/record/2019-29832-002

Integration: The Upside of Coming Down – Debriefing, Disrupting & Dark Journeys

Read the article:

https://chacruna.net/integration-the-upside-of-coming-down-part-two-debriefing-disrupting-dark-journeys/

Education and Training for Clinicians and Beyond

SEPTEMBER 8, 2018 BY PSYCHEDELICS TODAY

Rapid Depression Remission and the “Therapeutic Bends” with Ketamine-Assisted Psychotherapy

By Dr. Jessica Katzman

Read the article: https://psychedelicstoday.com/2018/09/08/rapid-depression-remission-therapeutic-bends-ketamine-assisted-psychotherapy/

Improving Ketamine Mileage

Ideal ketamine treatment is in a safe and supervised setting. This article highlights some simple ways to get the most out of every ketamine treatment.

Read the article: https://psychedelic.support/resources/improving-ketamine-mileage/

Synthesizing the Evidence for Ketamine and Esketamine in Treatment-Resistant Depression: An International Expert Opinion on the Available Evidence and Implementation

Read the article: https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2020.20081251?journalCode=ajp

Efficacy, Safety, and Durability of Repeated Ketamine Infusions for Comorbid Posttraumatic Stress Disorder and Treatment-Resistant Depression

Read the article: https://ajp.psychiatryonline.org/doi/abs/10.1176/appi.ajp.2020.20081251?journalCode=ajp

The Psychedelic Revolution Is Coming. Psychiatry May Never Be the Same.

Psilocybin and MDMA are poised to be the hottest new therapeutics since Prozac. Universities want in, and so does Wall Street. Some worry a push to loosen access could bring unintended consequences.

Read the Article in www.nytimes.com

The American Society of Ketamine Physicians, Psychotherapists, and Practitioners is a non-profit group of professionals dedicated to the safe clinical use of ketamine for mental health disorders and pain conditions.  The ASKP3 has set standards, and ethical guidelines, for the practice in the theraputic use of ketamine.

askp.org

KETAMINE TREATMENT FOR DEPRESSION: OPPORTUNITIES FOR CLINICAL INNOVATION AND ETHICAL FORESIGHT

Singh, Ilina et al. Ketamine treatment for depression: opportunities for clinical innovation and ethical foresight. The Lancet Psychiatry, Volume 4 , Issue 5 , 419 – 42.

A review and analysis of ethical considerations in off-label ketamine use for severe, treatment-resistant depression, and a review of the drug’s safety profile.

Read the article on TheLancet.com

A Time Magazine cover story from 2017, New Hope for Depression, explores one of the latest developments in treatment: ketamine hydrochloride. Read the article on Time.com

A CONSENSUS STATEMENT ON THE USE OF KETAMINE IN THE TREATMENT OF MOOD DISORDERS

Sanacora G, Frye MA, McDonald W, et al. A Consensus Statement on the Use of Ketamine in the Treatment of Mood Disorders. JAMA Psychiatry. 2017;74(4):399–405. doi:10.1001/jamapsychiatry.2017.0080

Studies on Ketamine hydrochloride’s ability to produce rapid and robust antidepressant effects in patients with mood and anxiety disorders that were previously resistant to treatment.

Read article on JAMA

EFFICACY OF INTRAVENOUS KETAMINE FOR TREATMENT OF CHRONIC POSTTRAUMATIC STRESS DISORDER: A RANDOMIZED CLINICAL TRIAL

Feder A, Parides MK, Murrough JW, et al. Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress DisorderA Randomized Clinical Trial. JAMA Psychiatry. 2014;71(6):681–688. doi:10.1001/jamapsychiatry.2014.62

Clinical study which tested the efficacy and safety of a single intravenous subanesthetic dose of ketamine for the treatment of PTSD.

Greater reduction of PTSD symptoms following treatment with ketamine was evident in both crossover and first-period analyses, and remained significant after adjusting for baseline and 24-hour depressive symptom severity.

Ketamine was generally well tolerated without clinically significant persistent dissociative symptoms.

This study provides the first evidence for rapid reduction in symptom severity following ketamine infusion in patients with chronic PTSD.

Read article on JAMA